General Cell Based Assays
Abcam Alkaline Phosphatase Assay Kit (Colorimetric)
Alkaline Phosphatase Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam ATP Assay Kit (Colorimetric/Fluorometric)
ATP Assay Kit (Colorimetric/Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Urea Assay Kit
Urea Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam LDH Assay Kit¿(Cytotoxicity)
LDH Assay Kit¿(Cytotoxicity)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Autophagy Assay Kit
Autophagy Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx cAMP Hunter eXpress GRM2 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0148E2CP23L)
The cAMP Hunter GRM2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. L-glutamate) based activation of GRM2 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GRM2, a naturally Gi/Go coupled GPCR. Upon activation of GRM2, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx InCELL Hunter eXpress PYK2 Kinase Binding Assay, 2pl Kit. (96-0042E15CP0M)
The InCELL Hunter eXpress PYK2 Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of PYK2 via detection of PYK2 levels. This product uses EFC technology. The cell line included overexpresses PYK2 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical NFAT InhIbItr 10mg
A peptide inhibitor of NFAT; binds to the NFAT recognition site on calcineurin (IC50 = 25 pM) but does not inhibit calcineurin phosphatase activity at 100 µM; inhibits the dephosphorylation of NFAT in HEK293T lysates expressing NFAT1, -2, or -4; inhibits NFAT activation in RAW 264.7 macrophages, EA.hy926 endothelial cells, and isolated mouse thoracic aorta VSMCs (IC50s = 29.1, 30.2, and 45.7 µM, respectively, in reporter assays)
![Abcam Anti-Beta Arrestin 2 antibody [EPR25410-70].](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3718002-Logo.png-250.jpg){kind=logo}
Abcam Anti-Beta Arrestin 2 antibody [EPR25410-70].
Anti-Beta Arrestin 2 antibody [EPR25410-70].
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical DIhydroethIdIum 25mg
A fluorescent dye to monitor superoxide production; ex/em = 490/590 nm; has been used to detect ROS and intracellular superoxide in vitro
Eurofins Discoverx PathHunter eXpress HTR2C (VNV) U2OS β-Arrestin GPCR Assay, 2pl Kit. (93-0938E3CP19M)
The PathHunter HTR2C(VNV) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of HTR2C(VNV) GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2C(VNV) and EA-tagged β-Arrestin-2. Activation of HTR2C(VNV) stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress BRS3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0945E2CP2L)
The PathHunter BRS3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. bombesin) based activation of BRS3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BRS3 and EA-tagged β-Arrestin-2. Activation of BRS3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CNR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0959E2CP0L)
The PathHunter CNR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CP 55,940) based activation of CNR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CNR1 and EA-tagged β-Arrestin-2. Activation of CNR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR137 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0361E2ACP1L)
The PathHunter GPR137 (TM7SF1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR137 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR137 and EA-tagged β-Arrestin-2. Activation of GPR137 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.